January 6th, 2012 by RyanDuBosar in News
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Cephalosporins will be used in livestock only for very specific exceptions, after years of debate about the role of antibiotic resistance in farming and how it leads to new strains of microbes with the potential to shift into humans.
The FDA took this step to preserve the effectiveness of cephalosporin drugs for treating disease in humans, the agency announced in a press release.
In 2008, the FDA issued and then revoked an order that prohibited cephalosporins in food-producing animals with no exceptions. Three years later, the agency’s ban includes several exceptions:
–It doesn’t limit cephapirin, which the FDA doesn’t think contributes to antimicrobial resistance;
–Veterinarians will still be able to Read more »
*This blog post was originally published at ACP Internist*
October 10th, 2011 by RyanDuBosar in News
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Crucial drugs are running in short supply and patients are dying as a result.
Much of the problem stem from manufacturing problems that interrupt production. There may be only one or two companies making a drug, and when something happens such as contamination, it creates huge gaps. As a result, there’s been 213 drug shortages so far this year, or two more than all of the previous year.
The shortages have forced hospitals to resort to gray market purchases. These involved third parties that may corner the market on some drugs, and resell them at exorbitant mark-ups. The practice then fuels further shortages.
And this “new” crisis has been occurring for a decade. ACP Internist ran an article 10 years ago that could run in its pages today. Read more »
*This blog post was originally published at ACP Internist*
October 5th, 2011 by Paul Auerbach, M.D. in Research
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Diverticula are small outpouchings that develop at weak points along the wall of the colon (large bowel), probably because of high pressures associated with muscle contractions during the passage of stool. When these sacs become obstructed and/or inflamed (most frequently in middle-aged or elderly individuals), they enlarge and create pain and fever. Usually, the left lower quadrant is involved, because diverticula tend to form in the left-side portion of the colon (descending colon) more frequently than in the right-side portion (ascending colon) or horizontal connecting section (transverse colon). A ruptured diverticulum can cause a clinical picture much like that of a ruptured appendix, with pain in the left side of the abdomen instead of the right side. The victim should seek medical attention, and his diet be limited to clear fluids. Antibiotics (metronidazole, metronidazole combined with doxycycline, amoxicillin-clavulanate, trimethoprim-sulfamethoxazole, cefixime, ciprofloxacin, or cefpodoxime) should be administered if help is more than 24 hours away.
As the population ages, diverticulitis is expected to become more prevalent. In a recent article Read more »
This post, Diverticulitis Expected To Become More Prevalent In An Aging Population, was originally published on
Healthine.com by Paul Auerbach, M.D..
September 25th, 2011 by Toni Brayer, M.D. in Health Policy
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I spent the day today with 60 physicians and nurses at a symposium focused on quality improvement and reducing mortality from sepsis. Sepsis (overwhelming infection) is the number 1 cause of hospital deaths and the mortality rate can be as high as 60% if the patient goes into shock from infection. Survival depends upon thousands of independent pieces coming together in an organized way. A patient doesn’t come to the emergency department and say “I have sepsis”. He may arrive by ambulance or be brought in by a relative and simply feel weak, or confused or have a fever.
To make the diagnosis, the doctor or nurse has to be thinking sepsis is a possibility and it is critical to get the right tests and treatments within a very short time frame. There are complicated steps that must be taken quickly and the entire hospital team (lab, pharmacy, transport, doctors and nurses) must act Read more »
*This blog post was originally published at EverythingHealth*
September 8th, 2011 by Michael Kirsch, M.D. in Opinion
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A good friend of mine and Whistleblower reader contracted the sniffles and received a prescription for antibiotics at a local urgent care center. Nothing newsworthy here. So far this quotidian event sounds like a ‘dog bites man’ story. Had antibiotics been denied, this would have been ‘man bites dog’, as this denial would be a radical departure of standard medical practice, particularly in the urgent care universe.
No doubt, my friend was not assigned the dismissive diagnosis of ‘the sniffles’, but was likely given a more ominous diagnosis of ‘acute upper respiratory infection’, a term that sounds so serious that he might have feared that a 911 call had already been made.
Why are antibiotics prescribed so casually and so frequently? Read more »
*This blog post was originally published at MD Whistleblower*
