December 13th, 2011 by Peggy Polaneczky, M.D. in News
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After cautiously clearing Yaz for continued use Thursday, an FDA Advisory Panel Friday addressed post-marketing data showing similarly increased blood clot risks among users of the contraceptive patch. The committee, after having been clearly quite extensively briefed, heard testimony from Ortho Evra’s manufacturer and experts in epidemiology, gynecology and hematology. They also heard moving testimony about a young woman who died from a massive pulmonary embolism while using the Nuvaring, whose parents argued that not only the Patch, but most of the newer methods carry an increased clot risk that no woman should be allowed to take without being adequately informed.
The committee ruled that despite limitations of the data, the patch most likely carried a 1.5 times relative risk of blood clots compared to 2nd generation levonogestrel pills, but not necessarily higher than that of newer pills containing 3rd and 4th generation progestins and drosperinone. With a few dissenters, the committee voted to allow the Patch to stay on the market, but asked for Read more »
*This blog post was originally published at The Blog That Ate Manhattan*
October 30th, 2011 by John Mandrola, M.D. in Research
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You don’t want this…
When it comes to the risk of stroke in atrial fibrillation, it pays to be a boy. Sorry, ladies.
An important question came up on my recent post on AF and stroke.
Why does being female give you an automatic point on CHADS2-VASc? I keep seeing it, but I don’t see why that is.
It doesn’t seem intuitive that female AF patients should have more strokes. Why? AF should equal AF.
But it does matter. When it comes to AF and stroke, women are very different.
Here are three references that support the fact that female gender increases the risk of stroke in AF.
–First: Read more »
*This blog post was originally published at Dr John M*
October 19th, 2009 by Happy Hospitalist in Better Health Network, True Stories
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I have a patient that comes in every so often that demands a PICC line (peripherally inserted central catheter). PICC lines are convenient for patients and nurses and doctors because they can be used to obtain blood without needing to stick the patient on a daily basis. They can be kept in for weeks and weeks and weeks with proper care. They can maintain adequate IV access when old ladies and drug addicts present with poor veins. Often they save the patient during acute decompensations of their critical illness. However, they come with frequent complications. I have had my share of patients return to the hospital with sepsis from their PICC line. Read more »
*This blog post was originally published at A Happy Hospitalist*
