November 28th, 2011 by Berci in Expert Interviews, Research
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The third edition of The Case for Personalized Medicine (PDF) was released a week ago and I had a chance to do an interview with Edward Abrahams, Ph.D. of the Personalized Medicine Coalition. The new edition is a primer that highlights the progress in the field of personalized medicine for policymakers, researchers, and business leaders.
- How many prominent examples of personalized medicine might we have next year?
It’s impossible for us to know how many prominent examples of personalized medicine products will be available a year from now, but we project that the rapid acceleration in the number of new products coming onto the market will continue. When we published the first edition of The Case for Personalized Medicine in 2006 – there were only 13 available products; when we published the second edition in 2009, there were 37 products available, and now, in 2011, there are 72.
- Sometimes lecturers use two numbers: 7 billion and 3 billion referring to the mass sequencing of everyone’s DNA in the world. When could it happen, what is your estimation? Read more »
*This blog post was originally published at ScienceRoll*
November 5th, 2011 by MuinKhouryMDPhD in Opinion, Research
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The popular proverbial saying “you cannot have your cake and eat it too” implies that one cannot consume something and preserve it at the same time–in other words, we cannot have it both ways. Well, for once, maybe we can have our cake–our whole genome sequence (WGS)–and eat it too. I believe having our WGS and consuming it in small bite sizes over a lifetime may be the only way to integrate it into medicine and public health.
Rapid advances in genomic sequencing technologies are making the possibility of reliable and affordable whole genome sequencing (WGS) a reality in the next few years. We all carry about 6 billion base pairs of DNA in each of our cells, with 5-10 million inherited variants that are different among us. This genetic variation along with environmental influences provides a blueprint for health throughout the life span, and is related to virtually every disease of public health significance. There is definite interest among the public and scientists about the personal utility of this information. In a recent survey by Nature, attitudes towards genome sequencing were explored among a sample dominated by scientists and professionals from medicine and public health. Although only 18.2% of respondents had had their genome sequenced or analyzed, 2/3 of those who had not reported they would take the opportunity should it arise. Curiosity was reported as the main single factor influencing respondents.
Can this information be useful today in improving medical care and preventing disease? Read more »
*This blog post was originally published at Genomics and Health Impact Blog*
August 23rd, 2011 by Berci in Opinion
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There is a very interesting thread on Quora. Users want to find the most iconic scientific image ever. It might sound like an easy job but it’s truly not. My vote is for the Watson-Crick DNA double helix photo. What is yours?
*This blog post was originally published at ScienceRoll*
August 13th, 2011 by RyanDuBosar in Research
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British researchers identified a faulty gene associated with a one-in-11 chance of developing ovarian cancer, and they think drugs for breast cancer might also work in these women.
Researchers from England’s Institute of Cancer Research reported that they compared DNA from women from 911 families with ovarian and breast cancer and to a control group of 1,060 people from the general population.
They found eight gene faults in theRAD51Dgene in women with cancer, compared with one in the control group. TheRAD51Dgene repairs damaged DNA, and when it’s faulty, cells are more likely to turn cancerous.
Results appear Read more »
*This blog post was originally published at ACP Internist*
August 6th, 2011 by Peggy Polaneczky, M.D. in Medical Art, News
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If your DNA determines who you are, and defines both your strengths and limitations, then you could say we all live our lives with a pre-dealt deck of cards.
That’s the premise of a new card game on display as part of the Talk to Me exhibit which opened at MOMA this week.
Players send in swabs of saliva; the designers send it out to be analyzed and then generate a customized 50-card deck from each player’s specific DNA…The deck allows players to become shadow versions of themselves, with all their genetic cards on the table, and in the game, as in reality, life depends on how the cards are played, not on which cards are dealt. The effects of any trait depend Read more »
*This blog post was originally published at The Blog That Ate Manhattan*
