December 26th, 2009 by Jonathan Foulds, Ph.D. in Better Health Network, Health Tips, Research
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I was recently asked to review a new textbook on Nicotine Psychopharmacology, containing 18 very thorough chapters describing the latest evidence on the effects of smoking and nicotine on the brain and behavior. Much of it, though interesting, was a very heavy read. But it occurred to me that it might be useful to try to summarize what the 544 pages in this new book suggests about the effects of nicotine and the reasons smokers get addicted. So here is an attempt to describe how nicotine addiction works, in simplified terms.
When a smoker inhales nicotine from a cigarette, the drug is carried to the brain in highly concentrated form within around 10-15 seconds. The drug then Read more »
This post, How Cigarette Nicotine Affects The Brain, was originally published on
Healthine.com by Jonathan Foulds, Ph.D..
November 24th, 2009 by Jonathan Foulds, Ph.D. in Better Health Network, Health Tips, Research
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Nicotine withdrawal symptoms typically peak in the first week of abstinence and return to normal at around 3-4 weeks. It has long been known that certain nicotinic receptors (particularly the beta-2 subtype) are closely involved in nicotine addiction, and that smokers have a larger number of nicotine receptors in their brains than non-smokers. When the smoker quits, this large number of vacant, unstimulated receptors is believed to be involved in the resulting craving and distressing withdrawal (irritability, restlessness, depression, anxiety, poor concentration etc).
Earlier this year, a study published by Drs Kelly Cosgrove, Julie Staley and colleagues at Yale University, provided evidence on the time course of normalization of these receptors after quitting smoking. Read more »
This post, Quitting Smoking? Your Nicotine receptors Take Over A Month To Normalize, was originally published on
Healthine.com by Jonathan Foulds, Ph.D..
