October 30th, 2011 by John Mandrola, M.D. in Research
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You don’t want this…
When it comes to the risk of stroke in atrial fibrillation, it pays to be a boy. Sorry, ladies.
An important question came up on my recent post on AF and stroke.
Why does being female give you an automatic point on CHADS2-VASc? I keep seeing it, but I don’t see why that is.
It doesn’t seem intuitive that female AF patients should have more strokes. Why? AF should equal AF.
But it does matter. When it comes to AF and stroke, women are very different.
Here are three references that support the fact that female gender increases the risk of stroke in AF.
–First: Read more »
*This blog post was originally published at Dr John M*
October 27th, 2011 by HarvardHealth in Research
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“To everything there is a season, and a time to every purpose under heaven.”
That oft-quoted passage doesn’t apply just to rending and sewing, weeping and laughing, or gathering stones together. Your body has its own set of “seasons,” many of them following the turn of a complete day. Taking some medications at specific times of the day can help them work better. A new study suggests that blood pressure drugs taken at night might improve blood pressure and prevent more heart attacks and strokes than taking the same medications during the day.
Spanish researchers tested Read more »
*This blog post was originally published at Harvard Health Blog*
October 14th, 2011 by John Mandrola, M.D. in Opinion, Research
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The news wires for atrial fibrillation were abuzz this last week. The vigor and speed with which health news travels is striking.
Since 2.6 million Americans live with AF, my guess is that many are looking at the release of the Medtronic-sponsored TTOP-AF trial with anticipation. Here is a link to the press release. The trial purported to show benefits of Medtronic’s novel phased RF ablation system in treating persistent AF.
The study was small and released at a relatively small symposium in Venice, Italy. The TTOP-AF trial randomized 210 patients with persistent AF (including flutter) to either ablation with Medtronic’s ablation system or conventional therapy with drugs and cardioversions.
They found, not surprisingly, that AF ablation reduced AF burden. AF ablation significantly reduced AF burden in 55.8% percent of patients versus only 26% of those treated with conventional medical treatment. Editorial comment: That kind of data is pretty typical.
The problem with the study Read more »
*This blog post was originally published at Dr John M*
October 2nd, 2011 by DeborahSchwarzRPA in News
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Ventricular Assist Devices (VADs) are small pumps that take over the work of the heart in pumping the blood through the body. Patients who need a heart transplant, but for whom there is no donor heart available, might be given a VAD for what’s called a bridge-to-transplant while they wait for a donor.
PediMag, the pediatric version of the adult device, CentriMag, is an external device designed for short-term use in infants with heart failure. PediMag can also be used to support children after heart transplant surgery if they experience organ rejection and need time for their hearts to rest and heal, according to Jonathan M. Chen, MD, Surgical Director of Pediatric Heart Transplantation at Morgan Stanley Children’s Hospital of New York. Dr. Chen has extensive experience treating children with heart failure and has recently authored an account of his first successful use of the PediMag as a biventricular bridge-to-transplant in an infant.
The PediMag ventricular assist device is Read more »
*This blog post was originally published at Columbia University Department of Surgery Blog*
Distracted Driving: Studies of driving while talking on a cell phone may have overestimated the risk of car crashes, new research suggests, Amy Norton reports for Reuters Health.
